Entry Detail



General Information

Database ID:SKCM02068
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:LEPROT
Full Name:leptin receptor overlapping transcript
Category:mRNA
Synonyms:LEPR|OB-RGRP|OBRGRP|VPS55
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):65420587End Site(bp):65436007
Gene Summary:LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]).[supplied by OMIM, Jul 2010]
External Links:
Ensembl ID:ENSG00000213625
HGNC ID:HGNC:29477
Entrez Gene:54741



Expression Profile of LEPROT Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-140-5p
YES
YES
NO
hsa-miR-142-5p
YES
NO
YES
hsa-miR-17-5p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-22-3p
YES
YES
NO
hsa-miR-338-3p
YES
YES
NO
hsa-miR-340-5p
YES
YES
YES
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-376a-3p
YES
YES
NO
hsa-miR-376b-3p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
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