ctcRbase

Entry Detail

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General Information

Database ID: SKCM02072 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ATXN3 Full Name: ataxin 3 Category: mRNA Synonyms: AT3|ATX3|JOS|MJD|MJD1|SCA3 Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 92038652 End Site(bp): 92106621 Gene Summary: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016] External Links: Ensembl ID: ENSG00000066427 HGNC ID: HGNC:7106 Entrez Gene: 4287

Expression Profile of ATXN3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES NO YES hsa-miR-125b-5p YES NO YES hsa-miR-1271-5p NO YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-21-5p YES NO YES hsa-miR-25-3p YES YES YES hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-32-5p YES YES YES hsa-miR-342-3p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-365a-3p YES YES NO hsa-miR-367-3p YES YES YES hsa-miR-409-3p YES NO YES hsa-miR-487a-3p YES NO YES hsa-miR-488-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-543 YES NO YES hsa-miR-590-5p YES NO YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-9-5p YES NO YES hsa-miR-96-5p NO YES YES Display: