ctcRbase

Entry Detail

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General Information

Database ID: SKCM02101 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PRKD3 Full Name: protein kinase D3 Category: mRNA Synonyms: EPK2|PKC-NU|PKD3|PRKCN|nPKC-NU Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 37250502 End Site(bp): 37324808 Gene Summary: This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking. [provided by RefSeq, Jan 2015] External Links: Ensembl ID: ENSG00000115825 HGNC ID: HGNC:9408 Entrez Gene: 23683

Expression Profile of PRKD3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-137 YES YES YES hsa-miR-139-5p YES YES YES hsa-miR-1-3p YES YES NO hsa-miR-144-3p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-154-5p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-192-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-206 YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-215-5p YES YES NO hsa-miR-23a-3p YES NO YES hsa-miR-23b-3p YES NO YES hsa-miR-24-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-448 YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-486-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-613 YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-96-5p YES YES NO Display: