ctcRbase

Entry Detail

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General Information

Database ID: SKCM02140 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TAF12 Full Name: TATA-box binding protein associated factor 12 Category: mRNA Synonyms: TAF2J|TAFII20 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 28589323 End Site(bp): 28643085 Gene Summary: Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2008] External Links: Ensembl ID: ENSG00000120656 HGNC ID: HGNC:11545 Entrez Gene: 6883

Expression Profile of TAF12 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-137 YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-143-3p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-96-5p YES YES NO Display: