ctcRbase

Entry Detail

---



General Information

Database ID: SKCM02161 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PGGT1B Full Name: protein geranylgeranyltransferase type I subunit beta Category: mRNA Synonyms: BGGI|GGTI Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 115204012 End Site(bp): 115262872 Gene Summary: Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010] External Links: Ensembl ID: ENSG00000164219 HGNC ID: HGNC:8895 Entrez Gene: 5229

Expression Profile of PGGT1B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-1271-5p NO YES YES hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-139-5p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-149-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-219a-5p YES NO YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-599 YES YES NO hsa-miR-96-5p NO YES YES Display: