ctcRbase

Entry Detail

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General Information

Database ID: SKCM02223 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SIGMAR1 Full Name: sigma non-opioid intracellular receptor 1 Category: mRNA Synonyms: ALS16|DSMA2|OPRS1|SIG-1R|SR-BP|SR-BP1|SRBP|hSigmaR1|sigma1R Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 34634722 End Site(bp): 34637809 Gene Summary: This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013] External Links: Ensembl ID: ENSG00000147955 HGNC ID: HGNC:8157 Entrez Gene: 10280

Expression Profile of SIGMAR1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES NO YES hsa-miR-147a YES NO NO hsa-miR-153-3p YES YES YES hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-448 YES NO YES hsa-miR-491-5p YES YES NO hsa-miR-506-3p YES NO YES hsa-miR-7-5p YES YES NO hsa-miR-873-5p YES YES YES Display: