Entry Detail



General Information

Database ID:SKCM02306
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:GBE1
Full Name:1,4-alpha-glucan branching enzyme 1
Category:mRNA
Synonyms:APBD|GBE|GSD4
Chromosome:chr3
Strand:-
Coordinate:
Start Site(bp):81489699End Site(bp):81762161
Gene Summary:The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease). [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000114480
HGNC ID:HGNC:4180
Entrez Gene:2632



Expression Profile of GBE1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
YES
YES
NO
hsa-miR-135a-5p
YES
YES
NO
hsa-miR-135b-5p
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
YES
hsa-miR-153-3p
YES
YES
NO
hsa-miR-193a-3p
YES
YES
NO
hsa-miR-193b-3p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-221-3p
YES
YES
NO
hsa-miR-222-3p
YES
YES
NO
hsa-miR-22-3p
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-429
YES
YES
NO
hsa-miR-448
YES
YES
NO
hsa-miR-542-3p
YES
YES
NO
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