Entry Detail



General Information

Database ID:SKCM02308
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PLK4
Full Name:polo like kinase 4
Category:mRNA
Synonyms:MCCRP2|SAK|STK18
Chromosome:chr4
Strand:+
Coordinate:
Start Site(bp):127880861End Site(bp):127899195
Gene Summary:This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
External Links:
Ensembl ID:ENSG00000142731
HGNC ID:HGNC:11397
Entrez Gene:10733



Expression Profile of PLK4 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
NO
hsa-miR-154-5p
YES
YES
NO
hsa-miR-214-3p
YES
YES
NO
hsa-miR-219a-5p
YES
YES
NO
hsa-miR-338-3p
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-375
YES
YES
NO
hsa-miR-376a-3p
YES
YES
NO
hsa-miR-376b-3p
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-505-3p
YES
YES
NO
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