ctcRbase

Entry Detail

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General Information

Database ID: SKCM02311 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NFYB Full Name: nuclear transcription factor Y subunit beta Category: mRNA Synonyms: CBF-A|CBF-B|HAP3|NF-YB Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 104117077 End Site(bp): 104138289 Gene Summary: The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000120837 HGNC ID: HGNC:7805 Entrez Gene: 4801

Expression Profile of NFYB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-124-3p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-136-5p YES YES NO hsa-miR-137 YES NO YES hsa-miR-141-3p YES YES YES hsa-miR-143-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-216a-5p YES NO YES hsa-miR-216b-5p YES YES YES hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-32-5p YES YES NO hsa-miR-33a-5p YES YES YES hsa-miR-33b-5p YES YES YES hsa-miR-340-5p YES YES YES hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-381-3p YES NO YES hsa-miR-431-5p YES YES NO hsa-miR-433-3p YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-873-5p YES NO YES hsa-miR-875-5p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: