ctcRbase

Entry Detail

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General Information

Database ID: SKCM02320 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TTF1 Full Name: transcription termination factor 1 Category: mRNA Synonyms: TTF-1|TTF-I Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 132375548 End Site(bp): 132406851 Gene Summary: This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression. [provided by RefSeq, Apr 2011] External Links: Ensembl ID: ENSG00000125482 HGNC ID: HGNC:12397 Entrez Gene: 7270

Expression Profile of TTF1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-542-3p YES YES NO Display: