| ncRNA Symbol: | PARP2 |
| Full Name: | poly(ADP-ribose) polymerase 2 |
| Category: | mRNA |
| Synonyms: | ADPRT2|ADPRTL2|ADPRTL3|ARTD2|PARP-2|pADPRT-2 |
| Chromosome: | chr14 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 20343582 | End Site(bp): | 20357905 |
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| Gene Summary: | This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008] |
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