ctcRbase

Entry Detail

---



General Information

Database ID: SKCM02382 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CYP51A1 Full Name: cytochrome P450 family 51 subfamily A member 1 Category: mRNA Synonyms: CP51|CYP51|CYPL1|LDM|P450-14DM|P450L1 Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 92112151 End Site(bp): 92142952 Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] External Links: Ensembl ID: ENSG00000001630 HGNC ID: HGNC:2649 Entrez Gene: 1595

Expression Profile of CYP51A1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1298-5p YES NO YES hsa-miR-136-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-876-5p YES YES NO Display: