ctcRbase

Entry Detail

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General Information

Database ID: SKCM02404 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: UGDH Full Name: UDP-glucose 6-dehydrogenase Category: mRNA Synonyms: GDH|UDP-GlcDH|UDPGDH|UGD Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 39498755 End Site(bp): 39528311 Gene Summary: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] External Links: Ensembl ID: ENSG00000109814 HGNC ID: HGNC:12525 Entrez Gene: 7358

Expression Profile of UGDH Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-149-5p YES YES NO hsa-miR-17-5p YES NO YES hsa-miR-204-5p YES YES NO hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-211-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-519d-3p YES NO YES hsa-miR-542-3p YES YES NO hsa-miR-93-5p YES NO YES Display: