ctcRbase

Entry Detail

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General Information

Database ID: SKCM02499 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CRADD Full Name: CASP2 and RIPK1 domain containing adaptor with death domain Category: mRNA Synonyms: MRT34|RAIDD Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 93677375 End Site(bp): 93894840 Gene Summary: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] External Links: Ensembl ID: ENSG00000169372 HGNC ID: HGNC:2340 Entrez Gene: 8738

Expression Profile of CRADD Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-495-3p YES YES NO Display: