ctcRbase

Entry Detail

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General Information

Database ID: SKCM02502 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: UBE2E3 Full Name: ubiquitin conjugating enzyme E2 E3 Category: mRNA Synonyms: UBCH9|UbcM2 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 180967248 End Site(bp): 181076585 Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013] External Links: Ensembl ID: ENSG00000170035 HGNC ID: HGNC:12479 Entrez Gene: 10477

Expression Profile of UBE2E3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-139-5p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-143-3p YES YES YES hsa-miR-150-5p YES NO YES hsa-miR-186-5p YES YES NO hsa-miR-205-5p YES NO YES hsa-miR-217 NO YES YES hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-362-5p YES NO YES hsa-miR-369-3p YES NO YES hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-377-3p YES NO YES hsa-miR-379-5p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-384 YES YES YES hsa-miR-411-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-532-3p YES NO YES hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-708-5p YES YES NO Display: