ctcRbase

Entry Detail

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General Information

Database ID: SKCM02505 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DNAJA3 Full Name: DnaJ heat shock protein family (Hsp40) member A3 Category: mRNA Synonyms: HCA57|TID1|hTID-1 Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 4425805 End Site(bp): 4456775 Gene Summary: This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000103423 HGNC ID: HGNC:11808 Entrez Gene: 9093

Expression Profile of DNAJA3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-421 YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-505-3p YES YES NO Display: