ctcRbase

Entry Detail

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General Information

Database ID: SKCM02514 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CAV2 Full Name: caveolin 2 Category: mRNA Synonyms: CAV Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 116287380 End Site(bp): 116508541 Gene Summary: The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011] External Links: Ensembl ID: ENSG00000105971 HGNC ID: HGNC:1528 Entrez Gene: 858

Expression Profile of CAV2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-144-3p YES YES NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-192-5p YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-215-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-339-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-346 YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-9-5p YES YES NO Display: