ctcRbase

Entry Detail

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General Information

Database ID: SKCM02530 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MKNK1 Full Name: MAP kinase interacting serine/threonine kinase 1 Category: mRNA Synonyms: MNK1 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 46557408 End Site(bp): 46616843 Gene Summary: This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012] External Links: Ensembl ID: ENSG00000079277 HGNC ID: HGNC:7110 Entrez Gene: 8569

Expression Profile of MKNK1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-149-5p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-218-5p YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-7-5p YES YES YES Display: