Entry Detail



General Information

Database ID:SKCM02536
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:CKAP2L
Full Name:cytoskeleton associated protein 2 like
Category:mRNA
Synonyms:-
Chromosome:chr2
Strand:-
Coordinate:
Start Site(bp):112736607End Site(bp):112764677
Gene Summary:The protein encoded by this gene is thought to be a mitotic spindle protein important to neural stem or progenitor cells. Mutations in this gene have been associated with spindle organization defects, including mitotic spindle defects, lagging chromosomes, and chromatin bridges. There is evidence that mutations in this gene are associated with Filippi syndrome, characterized by growth defects, microcephaly, intellectual disability, facial feature defects, and syndactyly. There is a pseudogene of this gene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
External Links:
Ensembl ID:ENSG00000169607
HGNC ID:HGNC:26877
Entrez Gene:150468



Expression Profile of CKAP2L Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-132-3p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-212-3p
YES
YES
NO
hsa-miR-326
YES
YES
YES
hsa-miR-330-5p
YES
YES
YES
hsa-miR-369-3p
YES
NO
YES
hsa-miR-376a-3p
YES
YES
NO
hsa-miR-376b-3p
YES
YES
NO
hsa-miR-429
YES
YES
NO
hsa-miR-653-5p
YES
YES
NO
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