Entry Detail



General Information

Database ID:SKCM02558
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:CTBP2
Full Name:C-terminal binding protein 2
Category:mRNA
Synonyms:-
Chromosome:chr10
Strand:-
Coordinate:
Start Site(bp):124984317End Site(bp):125161170
Gene Summary:This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
External Links:
Ensembl ID:ENSG00000175029
HGNC ID:HGNC:2495
Entrez Gene:1488



Expression Profile of CTBP2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
YES
YES
YES
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-129-5p
YES
YES
NO
hsa-miR-133a-3p
YES
YES
YES
hsa-miR-133b
YES
YES
YES
hsa-miR-141-3p
YES
YES
YES
hsa-miR-144-3p
YES
YES
YES
hsa-miR-153-3p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
YES
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-300
YES
NO
YES
hsa-miR-340-5p
YES
YES
NO
hsa-miR-342-3p
YES
YES
YES
hsa-miR-370-3p
YES
YES
YES
hsa-miR-377-3p
YES
YES
NO
hsa-miR-381-3p
YES
NO
YES
hsa-miR-448
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-758-3p
YES
YES
NO
hsa-miR-802
YES
NO
YES
hsa-miR-876-5p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
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