ctcRbase

Entry Detail

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General Information

Database ID: SKCM02575 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BUB1B Full Name: BUB1 mitotic checkpoint serine/threonine kinase B Category: mRNA Synonyms: BUB1beta|BUBR1|Bub1A|MAD3L|MVA1|SSK1|hBUBR1 Chromosome: chr15 Strand: + Coordinate: Start Site(bp): 40161023 End Site(bp): 40221136 Gene Summary: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000156970 HGNC ID: HGNC:1149 Entrez Gene: 701

Expression Profile of BUB1B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-142-3p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-543 YES YES NO hsa-miR-875-5p YES YES NO Display: