ctcRbase

Entry Detail

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General Information

Database ID: SKCM02580 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ABCD3 Full Name: ATP binding cassette subfamily D member 3 Category: mRNA Synonyms: ABC43|CBAS5|PMP70|PXMP1|ZWS2 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 94418455 End Site(bp): 94518666 Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000117528 HGNC ID: HGNC:67 Entrez Gene: 5825

Expression Profile of ABCD3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-136-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-142-3p YES NO YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-299-5p YES NO YES hsa-miR-300 YES YES YES hsa-miR-329-3p YES NO NO hsa-miR-362-3p YES NO NO hsa-miR-365a-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-375 YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES NO Display: