| ncRNA Symbol: | ERCC3 | | Full Name: | ERCC excision repair 3, TFIIH core complex helicase subunit | | Category: | mRNA | | Synonyms: | BTF2|GTF2H|RAD25|TFIIH|TTD2|XPB | | Chromosome: | chr2 | | Strand: | - | | Coordinate: | | Start Site(bp): | 127257290 | End Site(bp): | 127294176 |
| | Gene Summary: | This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] | | External Links: | |
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