ctcRbase

Entry Detail

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General Information

Database ID: SKCM02594 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MSH2 Full Name: mutS homolog 2 Category: mRNA Synonyms: COCA1|FCC1|HNPCC|HNPCC1|LCFS2|hMSH2 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 47402969 End Site(bp): 47562311 Gene Summary: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] External Links: Ensembl ID: ENSG00000095002 HGNC ID: HGNC:7325 Entrez Gene: 4436

Expression Profile of MSH2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-137 YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-21-5p YES YES YES hsa-miR-296-3p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-371a-5p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-590-5p YES YES YES Display: