ctcRbase

Entry Detail

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General Information

Database ID: SKCM02607 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NBN Full Name: nibrin Category: mRNA Synonyms: AT-V1|AT-V2|ATV|NBS|NBS1|P95 Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 89933336 End Site(bp): 90003228 Gene Summary: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000104320 HGNC ID: HGNC:7652 Entrez Gene: 4683

Expression Profile of NBN Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-136-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-625-5p YES NO NO Display: