Entry Detail



General Information

Database ID:SKCM02610
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:AP3M1
Full Name:adaptor related protein complex 3 subunit mu 1
Category:mRNA
Synonyms:-
Chromosome:chr10
Strand:-
Coordinate:
Start Site(bp):74120255End Site(bp):74151063
Gene Summary:The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]
External Links:
Ensembl ID:ENSG00000185009
HGNC ID:HGNC:569
Entrez Gene:26985



Expression Profile of AP3M1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7g-5p
YES
YES
NO
hsa-miR-103a-3p
YES
NO
YES
hsa-miR-107
YES
NO
YES
hsa-miR-124-3p
YES
NO
YES
hsa-miR-129-5p
YES
YES
NO
hsa-miR-130a-3p
YES
YES
NO
hsa-miR-130b-3p
YES
YES
NO
hsa-miR-135a-5p
YES
YES
NO
hsa-miR-135b-5p
YES
YES
NO
hsa-miR-136-5p
YES
YES
YES
hsa-miR-139-5p
YES
YES
YES
hsa-miR-15a-5p
YES
NO
YES
hsa-miR-15b-5p
YES
NO
YES
hsa-miR-16-5p
YES
NO
YES
hsa-miR-182-5p
YES
YES
YES
hsa-miR-183-5p
YES
YES
YES
hsa-miR-185-5p
YES
YES
NO
hsa-miR-195-5p
YES
NO
YES
hsa-miR-21-5p
YES
NO
YES
hsa-miR-217
YES
NO
YES
hsa-miR-218-5p
YES
YES
YES
hsa-miR-221-3p
YES
NO
YES
hsa-miR-222-3p
YES
NO
YES
hsa-miR-224-5p
YES
YES
NO
hsa-miR-29a-3p
YES
YES
YES
hsa-miR-29b-3p
YES
YES
YES
hsa-miR-29c-3p
YES
YES
YES
hsa-miR-301a-3p
YES
YES
NO
hsa-miR-301b-3p
YES
YES
NO
hsa-miR-30a-5p
YES
NO
YES
hsa-miR-30b-5p
YES
NO
YES
hsa-miR-30c-5p
YES
NO
YES
hsa-miR-30d-5p
YES
NO
YES
hsa-miR-30e-5p
YES
NO
YES
hsa-miR-320a
YES
NO
YES
hsa-miR-320b
YES
NO
YES
hsa-miR-320c
YES
NO
YES
hsa-miR-320d
YES
NO
YES
hsa-miR-340-5p
YES
YES
YES
hsa-miR-383-5p
YES
YES
NO
hsa-miR-384
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-424-5p
YES
NO
YES
hsa-miR-425-5p
YES
YES
YES
hsa-miR-454-3p
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-494-3p
YES
YES
NO
hsa-miR-495-3p
YES
YES
YES
hsa-miR-497-5p
YES
NO
YES
hsa-miR-506-3p
YES
NO
YES
hsa-miR-520f-3p
YES
NO
YES
hsa-miR-543
YES
YES
NO
hsa-miR-590-5p
YES
NO
YES
hsa-miR-873-5p
YES
YES
NO
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