ctcRbase

Entry Detail

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General Information

Database ID: SKCM02654 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: POGLUT1 Full Name: protein O-glucosyltransferase 1 Category: mRNA Synonyms: C3orf9|CLP46|KDELCL1|KTELC1|LGMD2Z|LGMDR21|MDS010|MDSRP|Rumi|hCLP46 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 119468938 End Site(bp): 119494708 Gene Summary: This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] External Links: Ensembl ID: ENSG00000163389 HGNC ID: HGNC:22954 Entrez Gene: 56983

Expression Profile of POGLUT1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-375 YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-422a YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-613 YES YES NO hsa-miR-98-5p YES NO YES Display: