| ncRNA Symbol: | ERAP2 |
| Full Name: | endoplasmic reticulum aminopeptidase 2 |
| Category: | mRNA |
| Synonyms: | L-RAP|LRAP |
| Chromosome: | chr5 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 96875939 | End Site(bp): | 96919716 |
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| Gene Summary: | This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016] |
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