Entry Detail



General Information

Database ID:SKCM02690
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:GSK3B
Full Name:glycogen synthase kinase 3 beta
Category:mRNA
Synonyms:-
Chromosome:chr3
Strand:-
Coordinate:
Start Site(bp):119821323End Site(bp):120094417
Gene Summary:The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]
External Links:
Ensembl ID:ENSG00000082701
HGNC ID:HGNC:4617
Entrez Gene:2932



Expression Profile of GSK3B Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
NO
YES
YES
hsa-miR-124-3p
NO
YES
YES
hsa-miR-128-3p
NO
YES
YES
hsa-miR-129-5p
NO
YES
YES
hsa-miR-1297
NO
YES
YES
hsa-miR-135a-5p
NO
YES
YES
hsa-miR-135b-5p
NO
YES
YES
hsa-miR-137
NO
YES
YES
hsa-miR-155-5p
NO
YES
YES
hsa-miR-199a-5p
YES
YES
YES
hsa-miR-199b-5p
YES
YES
YES
hsa-miR-219a-5p
NO
YES
YES
hsa-miR-23a-3p
NO
YES
YES
hsa-miR-23b-3p
NO
YES
YES
hsa-miR-24-3p
NO
YES
YES
hsa-miR-26a-5p
NO
YES
YES
hsa-miR-26b-5p
NO
YES
YES
hsa-miR-28-5p
NO
YES
YES
hsa-miR-29a-3p
NO
YES
YES
hsa-miR-29b-3p
NO
YES
YES
hsa-miR-29c-3p
NO
YES
YES
hsa-miR-410-3p
NO
YES
YES
hsa-miR-708-5p
NO
YES
YES
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