ctcRbase

Entry Detail

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General Information

Database ID: SKCM02698 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TMEM43 Full Name: transmembrane protein 43 Category: mRNA Synonyms: ARVC5|ARVD5|EDMD7|LUMA Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 14124940 End Site(bp): 14143679 Gene Summary: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq, Oct 2008] External Links: Ensembl ID: ENSG00000170876 HGNC ID: HGNC:28472 Entrez Gene: 79188

Expression Profile of TMEM43 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES YES hsa-miR-138-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-194-5p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-212-3p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-31-5p YES YES YES hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-7-5p YES YES NO Display: