ctcRbase

Entry Detail

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General Information

Database ID: SKCM02699 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: FN1 Full Name: fibronectin 1 Category: mRNA Synonyms: CIG|ED-B|FINC|FN|FNZ|GFND|GFND2|LETS|MSF|SMDCF Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 215360440 End Site(bp): 215436172 Gene Summary: This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016] External Links: Ensembl ID: ENSG00000115414 HGNC ID: HGNC:3778 Entrez Gene: 2335

Expression Profile of FN1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-144-3p YES YES NO hsa-miR-145-5p YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-206 YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-217 YES YES YES hsa-miR-24-3p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-429 YES YES YES hsa-miR-448 YES YES NO hsa-miR-613 YES YES YES hsa-miR-9-5p YES YES NO hsa-miR-96-5p YES YES YES Display: