Entry Detail



General Information

Database ID:SKCM02708
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:STAM
Full Name:signal transducing adaptor molecule
Category:mRNA
Synonyms:STAM-1|STAM1
Chromosome:chr10
Strand:+
Coordinate:
Start Site(bp):17644125End Site(bp):17715914
Gene Summary:This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
External Links:
Ensembl ID:ENSG00000136738
HGNC ID:HGNC:11357
Entrez Gene:8027



Expression Profile of STAM Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-128-3p
YES
YES
NO
hsa-miR-1298-5p
YES
NO
YES
hsa-miR-138-5p
YES
YES
NO
hsa-miR-142-3p
YES
YES
YES
hsa-miR-145-5p
YES
YES
YES
hsa-miR-185-5p
YES
YES
NO
hsa-miR-197-3p
YES
YES
NO
hsa-miR-205-5p
YES
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-25-3p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-32-5p
YES
YES
NO
hsa-miR-329-3p
YES
NO
NO
hsa-miR-362-3p
YES
NO
NO
hsa-miR-363-3p
YES
YES
NO
hsa-miR-367-3p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-487b-3p
YES
YES
NO
hsa-miR-488-3p
YES
YES
YES
hsa-miR-494-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
hsa-miR-653-5p
YES
YES
NO
hsa-miR-92a-3p
YES
YES
NO
hsa-miR-92b-3p
YES
YES
NO
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