ctcRbase

Entry Detail

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General Information

Database ID: SKCM02806 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SUCLA2 Full Name: succinate-CoA ligase ADP-forming beta subunit Category: mRNA Synonyms: A-BETA|A-SCS|MTDPS5|SCS-betaA Chromosome: chr13 Strand: - Coordinate: Start Site(bp): 47936491 End Site(bp): 48001354 Gene Summary: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000136143 HGNC ID: HGNC:11448 Entrez Gene: 8803

Expression Profile of SUCLA2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES NO NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-217 YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-384 YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-485-5p YES YES NO Display: