Entry Detail



General Information

Database ID:SKCM02874
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PHC1
Full Name:polyhomeotic homolog 1
Category:mRNA
Synonyms:EDR1|HPH1|MCPH11|RAE28
Chromosome:chr12
Strand:+
Coordinate:
Start Site(bp):8913896End Site(bp):8941467
Gene Summary:This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000111752
HGNC ID:HGNC:3182
Entrez Gene:1911



Expression Profile of PHC1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
NO
hsa-miR-329-3p
YES
YES
NO
hsa-miR-340-5p
YES
YES
YES
hsa-miR-410-3p
YES
YES
NO
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