Entry Detail



General Information

Database ID:SKCM02918
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:IQCB1
Full Name:IQ motif containing B1
Category:mRNA
Synonyms:NPHP5|PIQ|SLSN5
Chromosome:chr3
Strand:-
Coordinate:
Start Site(bp):121769763End Site(bp):121835079
Gene Summary:This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Jan 2016]
External Links:
Ensembl ID:ENSG00000173226
HGNC ID:HGNC:28949
Entrez Gene:9657



Expression Profile of IQCB1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
YES
hsa-let-7b-5p
YES
YES
YES
hsa-let-7c-5p
YES
YES
YES
hsa-let-7d-5p
YES
YES
YES
hsa-let-7e-5p
YES
YES
YES
hsa-let-7f-5p
YES
YES
YES
hsa-let-7g-5p
YES
YES
YES
hsa-let-7i-5p
YES
YES
YES
hsa-miR-147a
YES
NO
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-216b-5p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-328-3p
YES
YES
NO
hsa-miR-338-3p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-599
YES
YES
NO
hsa-miR-98-5p
YES
YES
YES
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