ctcRbase

Entry Detail

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General Information

Database ID: SKCM02977 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SPART Full Name: spartin Category: mRNA Synonyms: SPG20|TAHCCP1 Chromosome: chr13 Strand: - Coordinate: Start Site(bp): 36301638 End Site(bp): 36370180 Gene Summary: This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008] External Links: Ensembl ID: ENSG00000133104 HGNC ID: HGNC:18514 Entrez Gene: 23111

Expression Profile of SPART Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-21-5p YES NO YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-346 YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-384 YES NO YES hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES YES hsa-miR-448 YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-590-5p YES NO YES hsa-miR-93-5p YES YES NO hsa-miR-9-5p YES YES YES Display: