ctcRbase

Entry Detail

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General Information

Database ID: SKCM02978 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: VPS4B Full Name: vacuolar protein sorting 4 homolog B Category: mRNA Synonyms: MIG1|SKD1|SKD1B|VPS4-2 Chromosome: chr18 Strand: - Coordinate: Start Site(bp): 63389190 End Site(bp): 63422483 Gene Summary: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000119541 HGNC ID: HGNC:10895 Entrez Gene: 9525

Expression Profile of VPS4B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-144-3p YES YES YES hsa-miR-154-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-425-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-488-3p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: