ctcRbase

Entry Detail

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General Information

Database ID: SKCM02979 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PPP1R8 Full Name: protein phosphatase 1 regulatory subunit 8 Category: mRNA Synonyms: ARD-1|ARD1|NIPP-1|NIPP1|PRO2047 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 27830778 End Site(bp): 27851676 Gene Summary: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000117751 HGNC ID: HGNC:9296 Entrez Gene: 5511

Expression Profile of PPP1R8 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-101-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-665 YES NO YES hsa-miR-98-5p YES YES NO Display: