ctcRbase

Entry Detail

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General Information

Database ID: SKCM03024 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PFKM Full Name: phosphofructokinase, muscle Category: mRNA Synonyms: ATP-PFK|GSD7|PFK-1|PFK-A|PFK1|PFKA|PFKX|PPP1R122 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 48105139 End Site(bp): 48146404 Gene Summary: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009] External Links: Ensembl ID: ENSG00000152556 HGNC ID: HGNC:8877 Entrez Gene: 5213

Expression Profile of PFKM Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-128-3p NO YES YES hsa-miR-141-3p YES YES YES hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-21-5p YES YES YES hsa-miR-28-5p YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-383-5p YES NO YES hsa-miR-411-5p YES YES NO hsa-miR-542-3p YES YES YES hsa-miR-590-5p YES YES YES hsa-miR-668-3p YES NO YES hsa-miR-708-5p YES YES YES hsa-miR-877-5p YES NO YES hsa-miR-96-5p YES YES NO Display: