ctcRbase

Entry Detail

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General Information

Database ID: SKCM03051 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ECT2 Full Name: epithelial cell transforming 2 Category: mRNA Synonyms: ARHGEF31 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 172750682 End Site(bp): 172821474 Gene Summary: The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017] External Links: Ensembl ID: ENSG00000114346 HGNC ID: HGNC:3155 Entrez Gene: 1894

Expression Profile of ECT2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-372-3p YES NO YES hsa-miR-373-3p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-542-3p YES YES NO hsa-miR-96-5p YES YES NO Display: