| ncRNA Symbol: | MXD3 |
| Full Name: | MAX dimerization protein 3 |
| Category: | mRNA |
| Synonyms: | BHLHC13|MAD3|MYX |
| Chromosome: | chr5 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 177301461 | End Site(bp): | 177312757 |
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| Gene Summary: | This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008] |
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