ctcRbase

Entry Detail

---



General Information

Database ID: SKCM03089 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: LMAN1 Full Name: lectin, mannose binding 1 Category: mRNA Synonyms: ERGIC-53|ERGIC53|F5F8D|FMFD1|MCFD1|MR60|gp58 Chromosome: chr18 Strand: - Coordinate: Start Site(bp): 59327823 End Site(bp): 59359962 Gene Summary: The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015] External Links: Ensembl ID: ENSG00000074695 HGNC ID: HGNC:6631 Entrez Gene: 3998

Expression Profile of LMAN1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p NO YES YES hsa-miR-138-5p NO YES YES hsa-miR-1-3p YES YES NO hsa-miR-148a-3p NO YES YES hsa-miR-148b-3p NO YES YES hsa-miR-152-3p NO YES YES hsa-miR-153-3p NO YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p NO YES YES hsa-miR-200b-3p NO YES YES hsa-miR-200c-3p NO YES YES hsa-miR-206 YES YES NO hsa-miR-34a-5p NO YES YES hsa-miR-34c-5p NO YES YES hsa-miR-429 NO YES YES hsa-miR-449a NO YES YES hsa-miR-449b-5p NO YES YES hsa-miR-488-3p YES YES NO hsa-miR-613 YES YES NO hsa-miR-9-5p YES YES NO Display: