Entry Detail



General Information

Database ID:SKCM03091
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:RECQL
Full Name:RecQ like helicase
Category:mRNA
Synonyms:RECQL1|RecQ1
Chromosome:chr12
Strand:-
Coordinate:
Start Site(bp):21468911End Site(bp):21501669
Gene Summary:The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere maintenance, and is required for genotoxic stress resistance. Defects in this gene have been associated with several types of cancer. [provided by RefSeq, Jan 2017]
External Links:
Ensembl ID:ENSG00000004700
HGNC ID:HGNC:9948
Entrez Gene:5965



Expression Profile of RECQL Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
NO
hsa-miR-137
YES
YES
NO
hsa-miR-204-5p
YES
YES
NO
hsa-miR-208a-3p
YES
YES
NO
hsa-miR-208b-3p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-24-3p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-433-3p
YES
YES
YES
hsa-miR-506-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
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