Entry Detail



General Information

Database ID:SKCM03097
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ST8SIA1
Full Name:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Category:mRNA
Synonyms:GD3S|SIAT8|SIAT8-A|SIAT8A|ST8SiaI
Chromosome:chr12
Strand:-
Coordinate:
Start Site(bp):22063773End Site(bp):22437041
Gene Summary:Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]
External Links:
Ensembl ID:ENSG00000111728
HGNC ID:HGNC:10869
Entrez Gene:6489



Expression Profile of ST8SIA1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A