ctcRbase

Entry Detail

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General Information

Database ID: SKCM03100 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: GSS Full Name: glutathione synthetase Category: mRNA Synonyms: GSHS|HEL-S-64p|HEL-S-88n Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 34928430 End Site(bp): 34955817 Gene Summary: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000100983 HGNC ID: HGNC:4624 Entrez Gene: 2937

Expression Profile of GSS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-506-3p YES YES NO Display: