Entry Detail



General Information

Database ID:SKCM03114
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:TERF1
Full Name:telomeric repeat binding factor 1
Category:mRNA
Synonyms:PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1
Chromosome:chr8
Strand:+
Coordinate:
Start Site(bp):73008864End Site(bp):73048122
Gene Summary:This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000147601
HGNC ID:HGNC:11728
Entrez Gene:7013



Expression Profile of TERF1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-155-5p
YES
YES
YES
hsa-miR-186-5p
YES
YES
YES
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-361-5p
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-429
YES
YES
NO
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