ctcRbase

Entry Detail

---



General Information

Database ID: SKCM03136 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ABRAXAS1 Full Name: abraxas 1, BRCA1 A complex subunit Category: mRNA Synonyms: ABRA1|CCDC98|FAM175A Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 83459517 End Site(bp): 83523348 Gene Summary: This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] External Links: Ensembl ID: ENSG00000163322 HGNC ID: HGNC:25829 Entrez Gene: 84142

Expression Profile of ABRAXAS1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-140-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES NO Display: