ctcRbase

Entry Detail

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General Information

Database ID: SKCM03179 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DIABLO Full Name: diablo IAP-binding mitochondrial protein Category: mRNA Synonyms: DFNA64|SMAC Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 122207662 End Site(bp): 122227534 Gene Summary: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] External Links: Ensembl ID: ENSG00000184047 HGNC ID: NA Entrez Gene: 56616

Expression Profile of DIABLO Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-191-5p YES YES NO hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-324-5p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-487b-3p YES YES NO hsa-miR-499a-5p YES YES NO Display: