Entry Detail



General Information

Database ID:SKCM03188
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:RGS20
Full Name:regulator of G protein signaling 20
Category:mRNA
Synonyms:RGSZ1|ZGAP1|g(z)GAP|gz-GAP
Chromosome:chr8
Strand:+
Coordinate:
Start Site(bp):53851808End Site(bp):53959303
Gene Summary:The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
External Links:
Ensembl ID:ENSG00000147509
HGNC ID:HGNC:14600
Entrez Gene:8601



Expression Profile of RGS20 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1297
YES
YES
NO
hsa-miR-183-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-204-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-26a-5p
YES
YES
NO
hsa-miR-26b-5p
YES
YES
NO
hsa-miR-365a-3p
YES
YES
YES
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