Entry Detail



General Information

Database ID:SKCM03189
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:LIPA
Full Name:lipase A, lysosomal acid type
Category:mRNA
Synonyms:CESD|LAL
Chromosome:chr10
Strand:-
Coordinate:
Start Site(bp):89213569End Site(bp):89414557
Gene Summary:This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]
External Links:
Ensembl ID:ENSG00000107798
HGNC ID:HGNC:6617
Entrez Gene:3988



Expression Profile of LIPA Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-125a-5p
YES
YES
YES
hsa-miR-125b-5p
YES
YES
YES
hsa-miR-129-5p
YES
YES
NO
hsa-miR-130a-3p
YES
YES
NO
hsa-miR-130b-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
NO
hsa-miR-148a-3p
YES
YES
YES
hsa-miR-148b-3p
YES
YES
YES
hsa-miR-152-3p
YES
YES
YES
hsa-miR-192-5p
YES
YES
NO
hsa-miR-208a-3p
YES
YES
NO
hsa-miR-208b-3p
YES
YES
NO
hsa-miR-215-5p
YES
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-301a-3p
YES
YES
NO
hsa-miR-301b-3p
YES
YES
NO
hsa-miR-361-5p
YES
YES
NO
hsa-miR-370-3p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-448
YES
YES
NO
hsa-miR-454-3p
YES
YES
NO
hsa-miR-499a-5p
YES
YES
NO
hsa-miR-542-3p
YES
YES
NO
hsa-miR-875-5p
YES
YES
NO
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